github.com/AoU-Multiomics-Analysis/QuantifyQTLBurden/aFC

QuantifyQTLBurden

QuantifyQTLBurden estimates individual-level QTL burden from fine-mapped QTL effect sizes and genotypes. This repository also includes independent workflows for computing allelic fold change (aFC), because aFC estimation is the upstream step that produces the effect-size weights used by QTL burden quantification.

The workflows stay separate:

  1. Run the aFC workflows when starting from QTL mapping results, genotypes, expression BED files, and covariates.
  2. Run the Quantify

This is a companion discussion topic for the original entry at github.com/AoU-Multiomics-Analysis/QuantifyQTLBurden/aFC