pbs-analysis
This repository contains a pipelne for binning, estimating the background distribution, and calculating the probability of being signal for ChIP-seq and related datatypes.
Overall inputs:
BAM filename
Genome assembly
Bin size (minimum 5 kB)
Overall outputs:
Bed file with binned reads that are adjusted for mappability and copy number variations
Parameters file with estimated values defining a gamma distribution describing the background of the bed file. This file ca
This is a companion discussion topic for the original entry at github.com/broadinstitute/pbs-analysis