Aggregate Association Testing workflow runs aggregate association tests, using Burden, SKAT , fastSKAT , SMMAT , or SKAT-O  to aggregate a user-defined set of variants. Association tests are parallelized by segments within chromosomes.
Define segments splits the genome into segments and assigns each aggregate unit to a segment based on the position of its first variant. Note that number of segments refers to the whole genome, not a number of segments per chromosome. Association
This is a companion discussion topic for the original entry at github.com/sevenbridges-openworkflows/GENESIS-Aggregate-association-testing