TWAS Pipeline
This repository contains scripts and WDL workflows for running a Transcriptome-Wide Association Study (TWAS) using SuSiE fine-mapping results and GWAS summary statistics. The pipeline estimates SNP heritability, computes LD matrices, runs the TWAS analysis, and aggregates results across genes.
Repository Structure
TWAS/
├── scripts/ # R scripts used by the WDL workflows
├── workflows/ # WDL workflow definitions
├── envs/ # Dockerfile
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<small>This is a companion discussion topic for the original entry at <a href='https://dockstore.org/workflows/github.com/AoU-Multiomics-Analysis/TWAS/ConditionalRareTWAS'>github.com/AoU-Multiomics-Analysis/TWAS/ConditionalRareTWAS</a></small>