github.com/broadinstitute/long-read-pipelines/HmmIBD

Infer identity-by-descent (IBD) from a VCF. Step one pre-filters the VCF with bcftools (mask low-depth genotypes, recompute AN/AC/AF, trim unrepresented alleles/sites) into a BCF; step two runs hmmibd-rs (the Rust reimplementation of hmmIBD) on that BCF. The hmmibd-rs IBD segments and per-pair IBD fractions are returned as workflow outputs. Every hmmibd-rs tuning parameter is exposed with its upstream default so runs are fully configurable from Terra.


This is a companion discussion topic for the original entry at github.com/broadinstitute/long-read-pipelines/HmmIBD