Github.com/broadinstitute/popout/popout-dx

Automatic Tools and Workflows
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popout

popout

GPU-accelerated local ancestry inference at biobank scale — no reference panel required.

Feed it phased WGS from a large cohort and ancestry structure falls out of the joint distribution.


How it works

With 500K+ samples, the data is the reference panel. See docs/THEORY.md
for the full mathematical treatment. The pipeline:

  1. SEED — Randomized SVD on a SNP subset pro
This is a companion discussion topic for the original entry at github.com/broadinstitute/popout/popout-dx