BROAD Best Practices Somatic CNV Panel is used for creating a panel of normals (PON) given a set of normal samples.
Common Use Cases
For CNV discovery, the PON is created by running the initial coverage collection tools individually on a set of normal samples and combining the resulting copy ratio data using a dedicated PON creation tool . This produces a binary file that can be used as a PON. It is very important to use normal samples that are as technically similar as possible to the
This is a companion discussion topic for the original entry at github.com/sevenbridges-openworkflows/Broad-Best-Practice-Somatic-CNV-Workflows/GATK-Somatic-CNV-Panel-Workflow