github.com/UW-GAC/PRSmix_wdl/PRSmix

Automatic Tools and Workflows
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Introduction

The PRSmix package can be used to benchmark PRSs and compute the linear combination of trait-specific scores (PRSmix) and cross-trait scores (PRSmix+) to improve prediction accuracy.

NOTE:

  • You can run all steps or run each of them individually (set a_runStep1 or a_runStep2 to true or false).
  • Please make sure ALL optional FILES for all steps are provided even if you do not run that step (you can use a dummy file)

Manual

The pipeline contains 3 steps:

  • Harmonizing SNP ef
This is a companion discussion topic for the original entry at github.com/UW-GAC/PRSmix_wdl/PRSmix