PCAWG Broad variant calling workflow is developed by the Broad Institute (https://www.broadinstitute.org](https://www.broadinstitute.org)), it consists of software components calling somatic substitutions, indels and structural variations using uniformly aligned tumor / normal WGS sequences. The workflow has been dockerized and packaged using WDL workflow language, the source code is available on GitHub at: https://github.com/ICGC-TCGA-PanCancer/pcawg-broad-wgs-variant-caller.